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Milk Thistle Research

Milk thistle has been extensively researched and has proven to be safe even in large dosages. It is currently used to treat liver cirrhosis, alcoholic hepatitis, viral hepatitis, and protect the liver in general.

Milk Thistle contains silymarin, which is made up of several chemicals with silibinin—believed to be the most active as a powerful antioxidant that protects the liver from toxins binding to liver cells, and stimulates liver cells to regenerate. It is generally used to help protect the liver when patients are taking over-the-counter and prescription medicine that can have an adverse effect on the liver. Acetomenophen, or Tylenol, is one example of a drug that is shown to be harsh on the liver.

There are numerous randomized, double-blind, placebo controlled studies showing the benefits of milk thistle’s liver protecting benefits. A small sampling is listed below.

References 1. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physicians' Guide to Herbal Medicine. 3rd ed. Berlin, Germany: Springer-Verlag; 1998:215. 2. Muriel P, Garciapina T, Perez-Alvarez V, et al. Silymarin protects against paracetamol-induced lipid peroxidation and liver damage. J Appl Toxicol. 1992;12:439-442. 3. Paulova J, Dvorak M, Kolouch F, et al. Verification of the hepatoprotective and therapeutic effect of silymarin in experimental liver injury with tetrachloromethane in dogs [in Czech]. Vet Med (Praha). 1990;35:629-635. 4. Skakun NP, Moseichuk IP. Clinical pharmacology of legalon [in Russian]. Vrach Delo. 1988;5:5-10. 5. Tuchweber B, Sieck R, Trost W. Prevention of silybin of phalloidin-induced acute hepatotoxicity. Toxicol Appl Pharmacol. 1979;51:265-275. 6. Boari C, Montanari FM, Galletti GP, et al. Toxic occupational liver diseases. Therapeutic effects of silymarin [in Italian]. Minerva Med. 1981;72:2679-2688. 7. Szilard S, Szentogyorgyi D, Demeter I. Protective effect of Legalon in workers exposed to organic solvents. Acta Med Hung. 1988;45:249-256. 8. La Grange L, Wang M, Watkins R, et al. Protective effects of the flavonoid mixture, silymarin, on fetal rat brain and liver. J Ethnopharmacol. 1999;65:53-61. 9. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physicians' Guide to Herbal Medicine, 3rd ed. Berlin, Germany: Springer-Verlag; 1998:216. 10. Hikino H, Kiso Y. Natural products for liver disease. Econ Med Plant Res. 1988;2:39-72.

Read how milk thistle can help Arthritis sufferers here

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