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Schiff Knock-Out Research
Melatonin is a metabolic hormone made in the pineal gland, retina, and intestines. Melatonin is released into the blood stream by the pineal gland (which resides in the brain) to set your body’s biological clock and initiate sleep. Darkness stimulates the pineal gland and causes it to produce more melatonin. Daylight stops your body’s production of melatonin. Melatonin helps to promote healthy sleep patterns. Melatonin also protects cells from free radical damage, and directs the release of growth and sex hormones.
Theanine is believed to be the primary component of green tea that provides a relaxing effect. Theanine is an amino acid derivative of glutamine. Oral doses of 50 and 200 mg of theanine given to healthy volunteers promoted alpha brain wave production. Alpha waves are associated with a calm mental state. Theanine helps to induce a state of calm relaxation.
Valerian is known for its calming effects, and also used as a sleep aid. GABA (gamma-aminobutyric acid) is the major inhibitory neurotransmitter (message sender) in the brain. GABA plays a role in regulating sleep-wake cycles, and is involved in initiation of sleep. Melatonin, theanine and valerian extracts all interact with the GABA receptor.
MELATONIN RESEARCH
Research published in the October 2001 edition of the Journal of Clinical Endocrinology & Metabolism, conducted by researchers at MIT, showed that a .3 milligram dose of Melatonin was effective at restoring sleep in adults over 50. They further showed that higher doses were less effective at helping participants sleep through the night.
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